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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b164b485ce4017acece221e511648bde0633e7180d3ab876b6d92f28f5d0e84' 
  AND token = 'myOpp7CZmo5dD5QzJDKCeFUmiO1O0THBoJ5GVn/P6Dk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}