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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e747b0de1a5caa8317bb67bd7085a52a9abf032c044ddf591528d3f8ad347e2' 
  AND token = 'EFU/5kQ+mG18M60JYT3iOzX1nB+twpAO3dGb/8JeGV8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}