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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e011e2c2599903ae581a2c0973300369b932f2b7289d58b6f235afae23a375a4' 
  AND token = 'SrjO3UsWt11RrM7++Pi8bQqbStCdcag6VwuxZH1zoDc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}