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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fed6d62cc9b3b2beeb4afc119c85e9057030fe63e7aa3d66d8f2d810fd187956' 
  AND token = 'RC+Wp3JPcAQsRkSZGjB8Hi/n16ug+EiNrGrMzVMb3j8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}