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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0410c2f4d1600f2c6472a4fb02aac821807e92d00bb4245b6679ede8487fd34' 
  AND token = '1YJcAahhCQzrf98xd8bgCU2CtjJfg27JXJTOgmqmZeM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}