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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c0965515e82288fc986036ada7f527b4694dff0eaae6ae41eb477c3b287c430' 
  AND token = 'TOxvKn/VRqsl+8tpcgRnAyml8+GCX1EqC3eK5natcRA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}