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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd1b2edfe49f39f1c5bce71deb90b8377fbad0612ef4b32f622fbfbcda45ba1ec' 
  AND token = 'rRz/i4d6qNy6+3p+hnl+yB2uUsEOm+ebux4Y+CyGmzg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}