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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '595ff36ea59c23c3139e58fd0a39ba70d3162564330a99e05d192d938275592d' 
  AND token = '3v/EqIg2ybAlCPui7egQzOWyKnKymbJDwLyeJ5ZD6Pc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}