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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48dac8c4f577f0d729547c02e6ad1020ce2346bce284d9f9aa3911aecf85f254' 
  AND token = '9503bkyosNb7I0fnnykiQfEgaGhK9iQaPjR3xT9Stdk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}