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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'adc9a04eff73839585f8604419964d22517beb7c80cc183a2d000708621b7d21' 
  AND token = 'm46/4KG6N5/fnA/8iL/vwgwN5CpSg/pqDt5BfibLGx8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}