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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f938e24ce836e526853520c1bde528c1f0447bd1fb441005add66eb1371fe33f' 
  AND token = 'W3Znx+zKf5MsBRI+dFxM1QdGYq7aJA4XnG2pNBJdvO0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}