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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb6ffad8746a41ede5a6a941490f14dfa72af5f86b602517158709cb32ec5bd0' 
  AND token = '0YB8GJzMlqxNde4KmwQArbYk6/LCe8Fus2GbS4cwvD0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}