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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0f5c355c1d151cc240129b104ea0b936ed2bb84636e57bae0e3f6ba571ded66' 
  AND token = 'khXf5pYHm7TsJWA7CdOaBlcYhMf1g7VFWK25ZLO2WJE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}