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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35286c4e08a48530647f490b173118600753f451474e9a7e383283121d689bb4' 
  AND token = 'q21BaOnawebLFSLyNOewDfHfaFUl+suD8CBzZNtgvPU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}