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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16acd2c627d10c0e19c75b64804f932d481574004f49e6df48d323cb448fb4de' 
  AND token = 'UFBWAbslmg3Jz4Hzcma1M3Wegp6kmIWcwhZFQPnU2tA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}