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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b9cbeb03eacfaa4a17faabbf4021ff091d5dba95966fa02436e4712393df7277' 
  AND token = 'pUk411f2Wo5x1RsMcLq3d+K53ZHSaZ/wT0h+hB97yf8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}