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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45b6ca710d1b87ca532f57c51c0367f8d46ddf1e8af8abcf9436d6946ffc92d4' 
  AND token = 'kiDp9i4n8jL4ktUQU3AiNmKwzc6y6I1iQX0Dtw+KJew=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}