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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8103e67fe58a748bf890e840a5cb41e97c2fafe5cb2bea30b91b638be6ca683c' 
  AND token = 'cm9k+oZMLeaN+vaLbktDWUQwFIgUJSssXNcWb9bTu9Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}