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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a86412c73517d2d61a250f6201a15ef0bbb8116bc46c77ec6b22b2b52f4d499f' 
  AND token = 'p0kCs1qObFZqr4gR7v+DlBvdmjted1cYdDUl+KpeDJg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}