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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3df4368756430ac0466aba124d98efbff584e71b5f0f012ea5338456353700c3' 
  AND token = '24dtrqQuTE50ygY7cRPaWXa1ffO3Dzj0ydG2ig6RMtQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}