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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c1fb5e85b86f288fa79094c016b08abed41c8fc95bc960677b24a7497abf889' 
  AND token = '/r3i6jQZ9dlrpO5BBj3S4ba1ZDwAwdI6Of//abau0ys=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}