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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a0ccc69b152c3d6c6523e22190b5d66a9f35c4611379f94d0e4a065e0f178b8' 
  AND token = 'xobdgejqzAsaMaZFm3koZ3XA8wy+auWMkVhxIE2m+BE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}