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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b681fc7dc1b33b501d94c3fb66d651de02850dc561fab0a5b5b486a5a1fd761a' 
  AND token = 'wOLmwuC3/oPKkeVVOugWTFwOkFghkA/Hn9JBqlTVkTI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}