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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3080c543edc32f42f7d1d89c8ab427160ea400e9d2641a2ccbbc366b912bb4c' 
  AND token = 'mxzJ4rskm/napgWaJnNGJ+w0FPm8y5mAc6xpe+xLKSo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}