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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad5601e7af91af42bbd897ea99b9b2742a78577729bb61838d9fca1d84fbecad' 
  AND token = 'PYx6F5s5T83GGQJTWSz244a4+EYaDgOsKASLGEtdnLY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}