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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '357cdb2633003cc566732682e8fd2ec14b4f49da0b9b8c6fa2beb9b0a4e2d458' 
  AND token = 'B3qSIPZZoprbMdVmX5IePzQniIOCWmjT3+ilP8QUnOo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}