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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f45fecf01dd3d7a7c479a0120abcda95b15cb40b802654f6a60f02585479656' 
  AND token = 'vxH1V8jICGoCQYEPowpJMjxBDeWN4yrtnUbm7RqP4HY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}