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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c673ca1fd584b93db39648316cf333ea03b395ae6b165449a42caedce2415f28' 
  AND token = 'hwCwX6lo8UTl/6/qDvoyXeqlstvn4D2PUBFe3x/pUPs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}