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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '901c9c1f44f8b2f36df3629fc48da56e93f24d8ee5de64e4b2ec7f276f9d972d' 
  AND token = 'WRRrw2s4aE7ncP5FBYxUVhUvpAzdjBZ4fMQBTJ4ELvU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}