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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29f1afc27f1cf7725f0eca183d3997b9ceb2ef45e812ed719b82fe0b52fe4f94' 
  AND token = 'QTpmX1pXo6Wzy8rI2Q5pjPLD15hfJFzX5EC0rUuX2yo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}