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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1e5088b0138ccf4dea68b239f7d6f1ea25339b1f4e2b2e5d904a911437f4a00' 
  AND token = 'RZgRflgfNhLpGkuDytCAk1kx4OmIkec2UAK6i0Xken8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}