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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d0d4128f001f3c95eced742840aab8a5b42f4df7724fc431e333253073e2fe7' 
  AND token = 'Qk39ecZ/6hLj2JN0MgwyyyQUrFtvq/GdQkglZMH7Ddg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}