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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c245d9eef6e783d9cc159df43ac112e80acac1442ad4879dce7b12a7d380e86' 
  AND token = 'c2+ox6UPXlH1U5KtxDLA1PG6v1dQ3mKg5d5DTQCU43c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}