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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65c2e8351c495fffcd7332681f56c47e75c29192d4bfc49a94d4c3a07ccc80f7' 
  AND token = 'jLHZT3Vg8ZwAeeZ7fzvI9OlS7ot9Uvcf/85ehUFt4YA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}