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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e40f09c5640c365475c6c558fe1f830b17b690e3004476effa49ce488f374ae' 
  AND token = 'CmntRPW8qXnqJzTBWJxkjNQgrt1OWB2/pDoL3ssbzRA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}