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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef4f53dc55fa7d5120aa73f14d3a2da5bc40b8af0bd322ef97cc0f4a39acb23c' 
  AND token = '3+DAp9HhcbHbTe3L844H6skjkMhijkCAUVP3crsoM2I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}