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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '40ecad5df393a90bf90f5b67d18f21df4b8890f0988aa301b21aa5c3ce18ddc9' 
  AND token = 'ODi2HDsnf/Vw3AlNeBDttUT+LjzzPoLCA7xtNvU5/HM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}