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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b21cc9e1ba204fa25d4e9c8b8a9ff4586ac56626e5bfb4af47ae35476a70fb7' 
  AND token = 'xTv3m/7ADq3ehnPirh2Tdav375p1J1xdkZWMGgWLcv0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}