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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f39c770e7b22cb9bc3d29938242071206c6f76caae6e3591f2ff64eb93d906d8' 
  AND token = 'x81xeFSDr+QVjHd2Oap0DRg9OR7dZeOObnW06CNbeLk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}