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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e64a1420fc8011906190c129e39a8f484e7a57d9e057037227f7c1fdbb80873' 
  AND token = '2VSx5lk9D8UxdfNYVgUn+laWoY1hSL+YDbQYDQegi4w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}