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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00f3886c3fbcb68a9f6c1d0438ccdcadad5898601281efb0e43d0ad54ac01fd2' 
  AND token = 'tZKcc4lQ+Z/pglFKKV/c8OLZCsC3eJVeR/7Acc8HRdo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}