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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ccded532155ea5d8dddd033ef26c79118c0fc7e8fb291e534a72751ff9ce7c2' 
  AND token = 'D9dbzb9QSqeHN/kDm/sl4tGW0VJXIAxATdMyHSbXMNM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}