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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '288adacb6f4195a6c4e8c74dea2193acf58ce99f1191a9f67e65eadb07a2cab1' 
  AND token = 'ez6VBCyRO1gi8pnTVgZBGr93C6PxhY8KM+wakEl5uXc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}