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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '782866b4d6e118062d8b4f110bc75291584b7b3590ca8aed848c15c39d1ec399' 
  AND token = 'RKcy5UjQDnG9cdxOALZ9rwC1C1siQctEU9cPqD6rzjk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}