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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '97df4c95a768e270b1c2ff301ecb2d7849afdf20770e6cdb87e4c4ce888a96d4' 
  AND token = 'UzWypxA/tyUq/Ek3zAmjv7kPL/V8dahz4D8b5c3lkLA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}