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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3fb3930f453e3fa06d883e10b5e0af11ab24cac87c7eaa602a0e7dc6f4d77a80' 
  AND token = 'lxBn1orWDqg1kYN8thrtwX9eJ3tkg/EsQPXU5vTEMZ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}