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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c39d0ee4b57dd86a4465ac32f6f47a03149a098b9e9d0e07a47e51a310c3510' 
  AND token = 'TBsfoDIl/f4JbMCSbgjmQcxrttWP7NijpxUlCD1zzcQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}