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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e039a8d2ca71ef472baa99ca0f5ca92eda6d4261d8112723552a5648050f8059' 
  AND token = 'YycDb5l7JarcqFHGXly8eYuo0FOG0umxCYO0RYVamQ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}