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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'adf9cb17cde99dfb056c993c0e52128a1e013eb9afe773750021f718d1a3f900' 
  AND token = 'l4Rzqaj7WG+tCxOjZRz1+vU5JF51pkViFqc/t1dzTI4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}