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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72927e6b730d29b3f93d8179190d7d865a74f3a89687e227b61bd0a5ba3e6a7d' 
  AND token = '4fLLQTTqN8T6WDZsHRlXW2bRUMl820UjDXlKHfwcUPo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}